All News

Models of protein and DNA with text "DNA + Protein from Individual Fingerprints"
October 21, 2020

Fractionation of DNA and Protein from Individual Latent Fingerprints for Forensic Analysis

Abstract: Human touch samples represent a significant portion of forensic DNA casework. Yet, the generally low abundance of genetic material combined with the predominantly extracellular nature of DNA in these samples makes DNA-based forensic analysis exceptionally challenging. Human proteins present in these same touch samples offer an abundant and environmentally-robust alternative.... MORE
Stylized DNA helix with text "Signature Science's Krista Ternus Co-Authors Paper Published in PLOS"
August 7, 2020

Synthetic DNA and Biosecurity: Nuances of Predicting Pathogenicity and the Impetus for Novel Computational Approaches...

Dr. Krista Ternus worked with colleagues from Rice University and Texas A&M Health Science Center to author "Synthetic DNA and biosecurity: Nuances of predicting pathogenicity and the impetus for novel computational approaches for screening oligonucleotides." Overview: DNA synthesis technologies are enabling rapid advancements in the field of synthetic biology, which... MORE
Image of burning minivan over historical image of Wall Street bombing
June 30, 2020

New Methods, Same Motives: The IED Threat Requires a Resolute Response

THE EVOLVING THREAT The defeat of improvised explosive devices (IEDs) is, and has always been, a complex and constantly changing problem set. While the designs and methods used to build and deploy bombs have evolved, the desire of individuals and organizations to cause harm using IEDs has been constant, and... MORE
Flowchart of pathogen contamination and mitigation
June 16, 2020

Signature Science Team Authors Paper Published in “BMC Infectious Diseases”

Title: Simulating Transmission of ESKAPE Pathogens Plus C. difficile in Relevant Clinical Scenarios ABSTRACT BackgroundThe prevalence of healthcare-acquired infections (HAI) and rising levels of antimicrobial resistance places significant economic and public health burdens on modern healthcare systems. A group of highly drug resistant pathogens known as the ESKAPE pathogens, along with C. difficile, are... MORE
Stylized DNA helix with text "Signature Science's Forensics Lab Now Running STACS Casework"
May 11, 2020

Signature Science Becomes First Private Laboratory to Implement STACS® Casework

Signature Science’s casework laboratory joins public DNA crime laboratories across the country in implementing the intuitive laboratory information management system. AUSTIN, TEXAS – May 12, 2020 – Signature Science, LLC, has implemented STACS Casework DNA sample tracking and laboratory management software in its ANAB-accredited laboratory in Austin, TX. The decision... MORE
Illustration of cityscape, workflow diagram and the text "Fun GCAT"
April 20, 2020

Signature Science Team Awarded Phase 3 Funding for IARPA Fun GCAT Program

AUSTIN, TEXAS – April 21, 2020 – Signature Science, LLC has been selected to continue their support of the Intelligence Advanced Research Projects Activity (IARPA) in Phase 3 of the Functional Genomic and Computational Assessment of Threats (Fun GCAT) program. The research team will continue development of the Sequence to... MORE
Representations of protein, DNA, and a liquid drop combined and added to fingerprint slide
April 14, 2020

SigSci Scientists Co-author Study Published in “Forensic Science International: Genetics”

An Algorithm for Random Match Probability Calculation from Peptide Sequences Abstract: For the past three decades, forensic genetic investigations have focused on elucidating DNA signatures. While DNA has a number of desirable properties (e.g., presence in most biological materials, an amenable chemistry for analysis and well-developed statistics), DNA also has limitations.... MORE