About Signature Science
We serve government and commercial clients through a wide array of technical offerings that combine scientific rigor with proven quality assurance. Our expertise enhances the credibility and defensibility of government programs that provide for National Security, Public Safety and Security, and Health Security.
We Solve Problems Using Applied Science and Technology
Across many disciplines, our project teams are addressing some of the toughest challenges facing our local communities, our nation, and our world.
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A Compelling Work Environment and Culture
Signature Science employees benefit from a compelling work environment and corporate culture that are shaped by our pursuit of scientific innovation and service to our clients’ vital missions.
Tackling the Toughest Scientific Problems
We bring together the brightest minds from across the scientific disciplines to apply high-quality analysis and technical skills to meet new and developing challenges. Check our current openings to see where you fit.
News
Here’s what’s happening at Signature Science lately.
PLANES: Plausibility Analysis of Epidemiological Signals – Published in “PLoS One”
Abstract:Methods for reviewing epidemiological signals are necessary to building and maintaining data-driven public health capabilities. We have developed a novel approach for assessing the plausibility of infectious disease forecasts and surveillance data. The PLANES (PLausibility ANalysis of Epidemiological Signals) methodology is designed to … MORE
DNA Retrieved from Spent Shell Casing Presented as Evidence in Washington, DC Homicide Case
March 31, 2025 – Spent Shell Casing evidence submitted to Signature Science for DNA extraction and analysis was presented in a Washington, DC homicide trial this week. The analyst who processed the evidence delivered expert witness testimony. From the article: “The … MORE
Abstract: Background There is a new framework from the United States government for screening synthetic nucleic acids. Beginning in October of 2026, it calls for the screening of sequences 50 nucleotides or greater in length that are known to contribute to pathogenicity … MORE
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