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About Signature Science

We serve government and commercial clients through a wide array of technical offerings that combine scientific rigor with proven quality assurance. Our expertise enhances the credibility and defensibility of government programs that provide for National Security, Public Safety and Security, and Health Security.

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We Solve Problems Using Applied Science and Technology

Across many disciplines, our project teams are addressing some of the toughest challenges facing our local communities, our nation, and our world.

National Security
Public Safety and Security
Health Security

Join Our Team

We’re hiring

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A Compelling Work Environment and Culture

Signature Science employees benefit from a compelling work environment and corporate culture that are shaped by our pursuit of scientific innovation and service to our clients’ vital missions.

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Tackling the Toughest Scientific Problems

We bring together the brightest minds from across the scientific disciplines to apply high-quality analysis and technical skills to meet new and developing challenges. Check our current openings to see where you fit.

News

Here’s what’s happening at Signature Science lately.

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Horizon Newsletter – July 2025

We’re excited to launch our new dedicated forensics website designed to make working with Signature Science easier and more efficient than ever before!  The new website features: Comprehensive Forensic DNA Testing Services – In-depth information on our full suite of forensic DNA testing capabilities Streamlined … MORE

Image of two women smiling. Text reads 2025 SigSci Interns

Our Interns’ Summer with SigSci Forensics

Each summer, Signature Science, LLC welcomes at least one intern to assist with research in our Center for Advanced Genomics (CAG). The research and validations performed at the CAG are shared with the forensic community in the form of open-source … MORE

Green background image of DNA helix. Text reads An Evaluation of Biothreat Screening Tools

New Preprint: Inter-Tool Analysis of a NIST Dataset for Assessing Baseline Nucleic Acid Sequence Screening

Abstract: Nucleic acid synthesis is a dual-use technology that can benefit fields such as biology, medicine, and information storage. However, synthetic nucleic acids could also potentially be used negligently and ultimately cause harm, or be used with malicious intent to cause … MORE

SigSci Products

For detailed information on K9 training aids or laboratory proficiency testing, visit our product websites by clicking the appropriate link below.

Graphic of a bomb-sniffing dog being trained with the TrueScent logo and the text "TrueScent® K9 Training Aids" and a clickable link reading "LEARN MORE"
Photo of a technician working in a lab with the Text "Proficiency Testing" and a clickable link reading "LEARN MORE"